The peripheral autonomic neuropathy is a major complication of diabetes

  • The sweat glands are innervated by sympathetic unmyelinated nerve fibers of small diameter.
  • Exploring the sweat function was proposed to evaluate the severity of autonomic neuropathy. [1]
  • Neuropathic involvement of small fibers develops very early in patients with diabetes [2].
  • We find these impairments in other pathologies such as:

Peripheral Neuropathy Detection - Table 1

Amyloidosis Infections (Lyme Disease, HIV)
Autoimmune Diseases Certain Medications (Chemotherapy Drugs)
Inherited Disorders Alcoholism
  • SUDOSCAN technology allows to evaluate small fiber neuropathy through sweat function.

Symptoms of peripheral autonomic neuropathies

Peripheral Neuropathy Detection - Table 2

Stomach and intestines Constipation (hard stools) Diarrhea (loose stools) Feeling full after only a few bites (early satiety) Nausea after eating Problems controlling bowel movements Swallowing problems Swollen abdomen Vomiting of undigested food
Heart and lungs Abnormal heart rate or rhythm Blood pressure changes with position (orthostatic hypotension) Dizziness when standing High blood pressure Shortness of breath with activity or exercise (exercise intolerance)
Bladder Difficulty beginning to urinate Feeling of incomplete bladder emptying Leaking urine (incontinence)
Other Sweating too much or not enough Heat intolerance brought on with activity and exercise Sexual problems including erection problems Vaginal dryness and orgasm difficulties Sluggish pupillary reflex Weight loss without trying


[1] Low PA. Evaluation of sudomotor function. Clin Neurophysiol 2004;115:1506-13.[2] Tesfaye S, Chaturvedi N, Eaton SE, et al; EURODIAB Prospective Complications Study Group. Vascular risk factors and diabetic neuropathy. N Engl J Med 2005;352:341-50.

The advantage of
Neuropathy Early Detection

An innovative device for early detection and follow-up
of Autonomic and Small Fiber Neuropathy.

Simple results obtained in 3 minutes.